Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 12/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9870844 | 0.86 | ADCY1 (0.60) | ADCY1MAPK1CYP3A4SLC2A1TSHR | |
| SCHEMBL11117898 | 0.86 | ADCY1 (0.60) | ADCY1MAPK1CYP3A4SLC2A1TSHR | |
| SCHEMBL13639992 | 0.86 | ADCY1 (0.60) | ADCY1MAPK1CYP3A4SLC2A1TSHR | |
| SCHEMBL18601237 | 0.86 | ADCY1 (0.60) | ADCY1MAPK1CYP3A4SLC2A1TSHR | |
| SCHEMBL10020759 | 0.86 | ADCY1 (0.60) | ADCY1MAPK1CYP3A4SLC2A1TSHR | |
| SCHEMBL12028527 | 0.86 | ADCY1 (0.60) | ADCY1MAPK1CYP3A4SLC2A1TSHR | |
| SCHEMBL6469176 | 0.86 | ADCY1 (0.60) | ADCY1MAPK1CYP3A4SLC2A1TSHR | |
| SCHEMBL10690883 | 0.85 | ADCY1 (0.49) | ADCY1MAPK1CYP3A4SLC2A1TSHR | |
| SCHEMBL10685388 | 0.81 | ADCY1 (0.46) | ADCY1MAPK1CYP3A4SLC2A1TSHR | |
| SCHEMBL10685788 | 0.81 | ADCY1 (0.46) | ADCY1MAPK1CYP3A4SLC2A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782082-A | BRONCHODILATORS, ANTIHISTAMINES | SCHERING CORPORATION (US) | 1988-11-01 | — | — | US | disclosed |
| US-4517200-A | Method for treating allergic reactions with forskolin | SCHERING-PLOUGH CORPORATION (US) | 1985-05-14 | — | — | US | disclosed |