Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 6/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10853375 | 0.91 | TDP1 (0.51) | TDP1ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL20335097 | 0.85 | TDP1 (0.80) | TDP1ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL19288880 | 0.84 | TDP1 (0.82) | TDP1ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL8024125 | 0.84 | ALDH1A1 (0.64) | TDP1ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL5282818 | 0.83 | TDP1 (0.75) | TDP1ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL10862282 | 0.79 | LMNA (0.67) | TDP1ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL18143522 | 0.79 | ALDH1A1 (1.00) | TDP1ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL27188 | 0.79 | ALDH1A1 (1.00) | TDP1ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL18143537 | 0.79 | ALDH1A1 (0.62) | TDP1ALDH1A1CYP3A4HPGDHIF1A | |
| SCHEMBL11070229 | 0.79 | ALDH1A1 (0.73) | TDP1ALDH1A1CYP3A4HPGDHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |