Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 11/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916543 | 0.80 | PPARG (0.41) | PPARDPPARAGAAKMT2APPARG | |
| SCHEMBL10682878 | 0.79 | PPARD (0.38) | PPARDPPARAPPARGMAPTTSHR | |
| SCHEMBL10366671 | 0.76 | PPARD (0.35) | PPARDPPARAHRH4BPTF | |
| SCHEMBL10366676 | 0.76 | HRH4 (0.34) | PPARDPPARAHRH4BPTF | |
| SCHEMBL10682581 | 0.76 | KDM4E (0.39) | KMT2AMAPTNPSR1BRD4BPTF | |
| SCHEMBL10366469 | 0.75 | GAA (0.50) | GAAKMT2AMAPTRECQLNPSR1 | |
| SCHEMBL10366109 | 0.75 | PPARD (0.34) | PPARDPPARAPPARGMAPTTSHR | |
| SCHEMBL10366970 | 0.74 | SMN1; SMN2 (0.39) | PPARDPPARAPPARGTSHRNPSR1 | |
| SCHEMBL10367314 | 0.72 | MTNR1A (0.45) | PPARGMAPTBRD4BPTF | |
| SCHEMBL10368348 | 0.72 | KDM4E (0.41) | PPARDPPARAGAAKMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4783462-A | 3(2H)pyridazinone, and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1988-11-08 | — | — | US | claimed |
| EP-0193853-A2 | 3(2H)pyridazinone, process for its preparation and anti-allergic agent containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-09-10 | — | — | EP | claimed |