SCHEMBL10690724

SCHEMBL10690724

CNCc1cccc2c(C=O)csc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.47
IFNAR1 P17181 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
LMNA P02545 1/20 0.39
RECQL P46063 1/20 0.39
LTA4H P09960 1/20 0.36
PIM1 P11309 1/20 0.33
PIM3 Q86V86 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
TBXAS1 P24557 1/20 0.32
ERN1 O75460 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
TRIM24 O15164 1/20 0.30
TRIM33 Q9UPN9 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10687797 0.85 IFNAR1 (0.40) CYP2A6IFNAR1SMN1; SMN2LMNARECQL
SCHEMBL10689754 0.78 IFNAR1 (0.44) IFNAR1SMN1; SMN2LMNARECQLLTA4H
SCHEMBL10686690 0.78 IFNAR1 (0.44) CYP2A6IFNAR1SMN1; SMN2LMNARECQL
SCHEMBL10693094 0.77 IFNAR1 (0.44) CYP2A6IFNAR1SMN1; SMN2LMNARECQL
SCHEMBL10689257 0.76 CYP2A6 (0.44) CYP2A6IFNAR1SMN1; SMN2LMNARECQL
SCHEMBL9052072 0.76 IFNAR1 (0.43) IFNAR1SMN1; SMN2LMNARECQLLTA4H
SCHEMBL14156856 0.75 CYP2A6 (0.62) CYP2A6LMNAERN1CA1CA2
SCHEMBL10692786 0.74 CYP2A6 (0.56) CYP2A6SMN1; SMN2LMNAERN1TRIM24
SCHEMBL27380622 0.71 LMNA (0.48) IFNAR1SMN1; SMN2LMNARECQLLTA4H
SCHEMBL21828957 0.70 CYP2A6 (0.56) CYP2A6LMNAPIM1PIM3ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4737516-A FUNGICIDES SANDOZ LTD. (CH) 1988-04-12 US disclosed