Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IFNAR1 | P17181 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12281175 | 0.81 | CYP2A6 (0.40) | SMN1; SMN2CYP2A6MAPK9MAPK1MAPK8 | |
| SCHEMBL10692169 | 0.81 | CYP2A6 (0.36) | SMN1; SMN2CYP2A6MAPK9MAPK1MAPK8 | |
| SCHEMBL10689754 | 0.79 | IFNAR1 (0.44) | IFNAR1SMN1; SMN2LMNARECQLLTA4H | |
| SCHEMBL10686690 | 0.79 | IFNAR1 (0.44) | IFNAR1SMN1; SMN2LMNARECQLLTA4H | |
| SCHEMBL9052072 | 0.78 | IFNAR1 (0.43) | IFNAR1SMN1; SMN2LMNARECQLLTA4H | |
| SCHEMBL10689257 | 0.78 | CYP2A6 (0.44) | IFNAR1SMN1; SMN2LMNARECQLLTA4H | |
| SCHEMBL12321977 | 0.77 | CTSS (0.42) | — | |
| SCHEMBL10690724 | 0.77 | CYP2A6 (0.47) | IFNAR1SMN1; SMN2LMNARECQLLTA4H | |
| SCHEMBL10687797 | 0.77 | IFNAR1 (0.40) | IFNAR1SMN1; SMN2LMNARECQLLTA4H | |
| SCHEMBL10693338 | 0.75 | TSHR (0.45) | CYP2A6ALDH1A1MAPTPDE10AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4737516-A | FUNGICIDES | SANDOZ LTD. (CH) | 1988-04-12 | — | — | US | disclosed |