Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 11/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL711239 | 0.88 | CYP3A4 (0.52) | ALOX5CYP4F2CYP4A11ALDH1A1CYP3A4 | |
| SCHEMBL10693022 | 0.87 | LTA4H (0.54) | LTA4HALOX5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL27466587 | 0.84 | CYP3A4 (0.54) | ALOX5CYP4F2CYP4A11ALDH1A1CYP3A4 | |
| SCHEMBL2512047 | 0.80 | CYP3A4 (0.49) | CYP4F2CYP4A11ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL10649974 | 0.78 | PTGER2 (0.48) | ALDH1A1PPARGPPARA | |
| SCHEMBL6138915 | 0.77 | TSHR (0.44) | CYP4F2CYP4A11ALDH1A1PPARGPPARA | |
| SCHEMBL2773061 | 0.77 | CYP4F2 (0.68) | LTA4HALOX5CYP4F2CYP4A11 | |
| SCHEMBL5726907 | 0.77 | ALDH1A1 (0.53) | LTA4HALOX5CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL11088418 | 0.76 | CYP3A4 (0.47) | LTA4HCYP4F2CYP4A11ALDH1A1CYP3A4 | |
| Phenyl Ethanol SCHEMBL15170493 | 0.76 | CYP3A4 (0.54) | ALOX5CYP4F2CYP4A11ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769482-A | Cyano and thiocyano intermediates | ELI LILLY AND COMPANY (US) | 1988-09-06 | — | — | US | disclosed |
| EP-0108592-B1 | LEUKOTRIENE ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1987-09-30 | — | — | EP | disclosed |
| US-4661505-A | 4-(4-ACETYL-3-HYDROXY-2-PROPYLPHENOXY) ALKANOIC ACIDS, TETRAZOLES, AND DERIVATIVES | ELI LILLY AND COMPANY (US) | 1987-04-28 | — | — | US | disclosed |
| EP-0108592-A1 | Leukotriene antagonists | ELI LILLY AND COMPANY (US) | 1984-05-16 | — | — | EP | disclosed |