Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9279198 | 0.78 | HSD17B10 (0.53) | ALDH1A1KDM4EHSD17B10CYP1A2MAPT | |
| SCHEMBL10696450 | 0.76 | ALDH1A1 (0.31) | ALDH1A1MAPTGABRA1GABRB2TDP1 | |
| SCHEMBL10988570 | 0.76 | CDC7 (0.41) | ALDH1A1CDC7PLK4DYRK3JAK2 | |
| SCHEMBL10588572 | 0.75 | ALDH1A1 (0.36) | ALDH1A1KDM4ECYP1A2HPGDCYP3A4 | |
| SCHEMBL20819297 | 0.75 | RORC (0.48) | ALDH1A1KDM4EHSD17B10CYP3A4MAPT | |
| SCHEMBL317997 | 0.71 | TRPV1 (0.55) | ALDH1A1KDM4EHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL10824264 | 0.70 | MEN1 (0.39) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL17553923 | 0.69 | CDC7 (0.43) | ALDH1A1KDM4ECDC7PLK4DYRK3 | |
| SCHEMBL28790723 | 0.69 | KDM4E (0.36) | ALDH1A1KDM4EHSD17B10ROCK2ROCK1 | |
| SCHEMBL7332624 | 0.68 | SMN1; SMN2 (0.38) | ALDH1A1KDM4EHSD17B10CDK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4721797-A | Process for the preparation of N-acyl-N-alkyl-2,6-dialkyl-3-chloroanilines | CIBA-GEIGY CORPORATION (US) | 1988-01-26 | — | — | US | disclosed |
| US-4401833-A | Process for the preparation of 4-chloro-2,6-dialkylanilines | BAYER AKTIENGESELLSCHAFT (DE) | 1983-08-30 | — | — | US | disclosed |