Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689435 | 0.94 | RAD51 (0.61) | ALDH1A1KDM4EL3MBTL1LMNANPSR1 | |
| SCHEMBL8112450 | 0.88 | KDM4E (0.74) | ALDH1A1KDM4EL3MBTL1LMNANPSR1 | |
| SCHEMBL31070199 | 0.88 | KDM4E (0.74) | ALDH1A1KDM4EL3MBTL1LMNANPSR1 | |
| SCHEMBL14076263 | 0.83 | ALDH1A1 (0.73) | ALDH1A1KDM4EL3MBTL1LMNANPSR1 | |
| SCHEMBL10684481 | 0.82 | TDP1 (0.63) | ALDH1A1KDM4EL3MBTL1LMNANPSR1 | |
| SCHEMBL2867767 | 0.82 | MAPK14 (0.69) | ALDH1A1KDM4EL3MBTL1LMNANPSR1 | |
| SCHEMBL10689164 | 0.81 | ALDH1A1 (0.76) | ALDH1A1KDM4EL3MBTL1LMNANPSR1 | |
| SCHEMBL11770437 | 0.81 | KDM1A (0.56) | ALDH1A1KDM4EL3MBTL1LMNANPSR1 | |
| SCHEMBL10684777 | 0.79 | APP (0.52) | ALDH1A1KDM4ELMNANPSR1CYP3A4 | |
| SCHEMBL10681946 | 0.79 | MAPK14 (0.56) | ALDH1A1KDM4EL3MBTL1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760006-A | Photoconductive layer containing photoconductor, a binder and a sensitizing dyestuff on electroconductive support | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-26 | — | — | US | disclosed |
| EP-0166230-B1 | 2,3-BIS(DIALKYLAMINOPHENYL)QUINOXALINES AND THEIR USE IN ELECTROGRAPHIC RECORDING MATERIALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-04-06 | — | — | EP | disclosed |