Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10059739 | 0.87 | MAPT (0.44) | MAPTRXFP1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29348781 | 0.86 | HTT (0.41) | TRPV1MAPTRXFP1LMNATP53 | |
| SCHEMBL31537714 | 0.83 | ALDH1A1 (0.40) | MAPTRXFP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL31537633 | 0.82 | VHL (0.42) | MAPTRXFP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1344141 | 0.81 | TRPV1 (0.43) | TRPV1MPIPHOSPHO1MAPTRXFP1 | |
| SCHEMBL16812365 | 0.81 | ALDH1A1 (0.43) | TRPV1MPIPHOSPHO1MAPTRXFP1 | |
| SCHEMBL26601277 | 0.77 | KDM4E (0.47) | TRPV1MPIPHOSPHO1KDM4EALDH1A1 | |
| SCHEMBL30827615 | 0.77 | CYP3A4 (0.41) | MAPTALDH1A1LMNACYP1A2TDP1 | |
| SCHEMBL27250754 | 0.77 | FFAR4 (0.41) | TRPV1ALDH1A1TP53 | |
| SCHEMBL15327967 | 0.76 | KDM4E (0.63) | TRPV1MPIPHOSPHO1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259048-A2 | Chemical compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-09 | — | — | EP | disclosed |