Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.42 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4282578 | 0.84 | HTT (0.51) | LCKKITSRCMPIPHOSPHO1 | |
| SCHEMBL14018033 | 0.82 | PTGS2 (0.45) | KDM4EALDH1A1MAPTLMNATP53 | |
| SCHEMBL10691031 | 0.81 | TRPV1 (0.44) | TRPV1MPIPHOSPHO1GSK3AGSK3B | |
| SCHEMBL747392 | 0.80 | NOTUM (0.47) | LCKKITSRCKDM4EALDH1A1 | |
| SCHEMBL16812365 | 0.79 | ALDH1A1 (0.43) | TRPV1LCKKITSRCKDR | |
| SCHEMBL26601277 | 0.79 | KDM4E (0.47) | TRPV1MPIPHOSPHO1KDM4EALDH1A1 | |
| SCHEMBL9109139 | 0.79 | MMP8 (0.42) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13153504 | 0.79 | FAAH (0.38) | ALDH1A1MAPTMEN1KMT2ARXFP1 | |
| SCHEMBL3834300 | 0.79 | ALDH1A1 (0.40) | LCKKITSRCKDRKDM4E | |
| SCHEMBL2615405 | 0.78 | TDP1 (0.40) | TRPV1MPIPHOSPHO1GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8063055-B2 | Substituted pyridone compounds and methods of use | AMGEN INC. (US) | 2011-11-22 | — | — | US | disclosed |