Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 13/20 | 0.47 |
| ▸ | DRD2 | P14416 | 12/20 | 0.47 |
| ▸ | HTR7 | P34969 | 11/20 | 0.47 |
| ▸ | HTR6 | P50406 | 11/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL10691411 | 0.95 | HTR2A (0.46) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL10634163 | 0.77 | ACHE (0.60) | HTR2ADRD2HTR7HTR6HTR1A | |
| Hydrochloric Acid SCHEMBL10640530 | 0.77 | HTR2A (0.52) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL10972315 | 0.76 | DRD2 (0.54) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL11016952 | 0.76 | HTR2A (0.58) | HTR2ADRD2HTR7HTR6HTR1A | |
| Hydrochloric Acid SCHEMBL10638219 | 0.76 | ACHE (0.59) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL9473414 | 0.76 | HTR2A (0.42) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL10502596 | 0.76 | HTR2A (0.49) | HTR2ADRD2HTR7HTR6HTR1A | |
| SCHEMBL10502438 | 0.75 | DRD2 (0.48) | HTR2ADRD2HTR7HTR6 | |
| SCHEMBL10502409 | 0.75 | HTR2A (0.45) | HTR2ADRD2HTR7HTR6HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4788201-A | HYPOTENSIVE AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-11-29 | — | — | US | claimed |