Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.47 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691303 | 0.83 | POLB (0.46) | ABCG2POLBNTRK1NTRK2GAA | |
| SCHEMBL1917467 | 0.80 | RIPK1 (0.62) | PARP1RIPK1PKN1PKN2GAA | |
| SCHEMBL9125563 | 0.78 | RIPK1 (0.67) | PARP1RIPK1PKN1PKN2 | |
| SCHEMBL7478397 | 0.77 | PKN1 (0.59) | PARP1RIPK1PKN1PKN2GAA | |
| SCHEMBL12730392 | 0.76 | PKN1 (0.57) | PARP1RIPK1PKN1PKN2GAA | |
| SCHEMBL6841804 | 0.76 | PKN1 (0.57) | PARP1RIPK1PKN1PKN2GAA | |
| SCHEMBL15767242 | 0.76 | PKN1 (0.57) | RIPK1PKN1PKN2 | |
| SCHEMBL2845527 | 0.76 | RIPK1 (0.58) | PARP1RIPK1PKN1PKN2POLB | |
| SCHEMBL20106695 | 0.75 | POLB (0.78) | POLBNTRK1NTRK2 | |
| SCHEMBL939723 | 0.75 | RIPK1 (0.59) | PARP1RIPK1PKN1PKN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769384-A | ANTIULCER AGENTS | NIPPON SHINYAKU CO. LTD. (JP) | 1988-09-06 | — | — | US | disclosed |