Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | APC | P25054 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685754 | 0.89 | PGR (0.46) | PDE4DPGRALDH1A1HTTMEN1 | |
| SCHEMBL10684724 | 0.80 | PGR (0.44) | PDE4DPGRALDH1A1MEN1KMT2A | |
| SCHEMBL10683151 | 0.75 | PDE4D (0.50) | PDE4DPGRALDH1A1HTTMEN1 | |
| SCHEMBL10691334 | 0.71 | TSHR (0.47) | PRKDCCNR1CNR2ALDH1A1HTT | |
| SCHEMBL16899734 | 0.64 | KCNH2 (0.52) | CNR1CNR2POLB | |
| SCHEMBL8302888 | 0.63 | PGR (0.46) | PDE4DPGRALDH1A1MEN1KMT2A | |
| SCHEMBL578335 | 0.63 | SMN1; SMN2 (0.70) | CNR1CNR2ALDH1A1HTT | |
| SCHEMBL6818232 | 0.62 | SMN1; SMN2 (0.68) | CNR1CNR2ALDH1A1HTT | |
| SCHEMBL17160816 | 0.62 | SMN1; SMN2 (0.68) | CNR1CNR2ALDH1A1HTT | |
| SCHEMBL11735535 | 0.62 | SMN1; SMN2 (0.67) | PDE4DPDE4APDE4BPDE4CPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738961-A | FUNGICIDES | SANKYO COMPANY, LIMITED (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0072238-B1 | PYRIDAZINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN AGRICULTURAL COMPOSITIONS AND THE TREATMENT OF SEED AND PLANTS | SANKYO COMPANY LIMITED (JP) | 1985-11-06 | — | — | EP | disclosed |
| EP-0072238-A1 | Pyridazinone derivatives, their preparation and their use in agricultural compositions and the treatment of seed and plants | SANKYO COMPANY LIMITED (JP) | 1983-02-16 | — | — | EP | disclosed |