Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.54 |
| ▸ | CES1 | P23141 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834288 | 0.90 | KMT2A (0.45) | CES2CES1ALDH1A1NPC1RAB9A | |
| SCHEMBL9066574 | 0.84 | CES2 (0.59) | CES2CES1ALDH1A1CYP1A2RAB9A | |
| SCHEMBL11362358 | 0.81 | PARP10 (0.55) | CES2CES1ALDH1A1NPC1RAB9A | |
| SCHEMBL7585829 | 0.79 | TDP1 (0.48) | CES2CES1ALDH1A1CYP1A2KMT2A | |
| SCHEMBL4197237 | 0.78 | CES2 (0.69) | CES2CES1ALDH1A1CYP1A2NPC1 | |
| SCHEMBL1628567 | 0.77 | GAA (0.47) | ALDH1A1CYP1A2KMT2AMEN1PPARG | |
| SCHEMBL28197933 | 0.77 | TSHR (0.52) | CES2CES1ALDH1A1NPC1RAB9A | |
| Benzene SCHEMBL27641543 | 0.77 | TSHR (0.52) | CES2CES1ALDH1A1NPC1RAB9A | |
| SCHEMBL26712 | 0.77 | TSHR (0.52) | CES2CES1ALDH1A1NPC1RAB9A | |
| SCHEMBL8736770 | 0.76 | CES2 (0.67) | CES2CES1ALDH1A1CYP1A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268276-A1 | COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF INFECTIONS OF THE ORAL CAVITY | Indena S.p.A. (IT) | 2011-01-05 | — | — | EP | disclosed |
| WO-2009129926-A1 | COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF INFECTIONS OF THE ORAL CAVITY | INDENA S.P.A. (IT) | 2009-10-29 | — | — | WO | disclosed |