SCHEMBL1628567

SCHEMBL1628567

COC(Oc1ccccc1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
PKM P14618 1/20 0.47
CYP2C19 P33261 1/20 0.47
PPARG P37231 5/20 0.45
PPARA Q07869 5/20 0.45
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
KMT2A Q03164 3/20 0.43
HPGD P15428 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CA4 P22748 1/20 0.41
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
MEN1 O00255 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
PTGS1 P23219 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2464979 0.87 CYP1A2 (0.48) GAACYP1A2CYP2C9PKMCYP2C19
SCHEMBL28849410 0.85 LMNA (0.53) MTNR1AMTNR1BKMT2ASMN1; SMN2TSHR
SCHEMBL7669989 0.84 POLB (0.42) GAACYP1A2CYP2C9PKMCYP2C19
SCHEMBL8555116 0.82 CYP1A2 (0.36) GAACYP1A2CYP2C9PKMCYP2C19
SCHEMBL8892864 0.82 PPARA (0.51) CYP1A2CYP2C19PPARGPPARAKMT2A
SCHEMBL2834288 0.82 KMT2A (0.45) GAAMTNR1AMTNR1BKMT2ASMN1; SMN2
SCHEMBL9811688 0.82 PPARG (0.62) CYP1A2CYP2C19PPARGPPARASMN1; SMN2
SCHEMBL5197676 0.81 TSHR (0.47) GAAMTNR1AMTNR1BKMT2AHPGD
SCHEMBL4303183 0.80 MTNR1A (0.45) GAACYP1A2CYP2C9PKMCYP2C19
SCHEMBL9715374 0.80 PPARA (0.45) GAACYP1A2CYP2C9PKMCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0014651-B1 TALAMPICILLIN 2-METHOXYPHENOXY ACETATE, PROCESS FOR ITS PREPARATION AND MEDICAMENTS CONTAINING IT SANOFI S.A. (FR) 1982-08-04 EP claimed
CN-218653369-U Filtering and concentrating device for crude product of triphenylacetic acid 安徽有吉医药科技有限公司 2023-03-21 CN disclosed
CN-112471168-A Bactericide composition containing triphenyltin acetate and cyproconazole and application thereof 浙江禾本科技股份有限公司 2021-03-12 CN disclosed
EP-3079680-A2 COMPOSITIONS AND METHODS FOR TREATING, PREVENTING AND DIAGNOSING CANCER AND OTHER PROLIFERATIVE DISORDERS Angiogenex, Inc. (US) 2016-10-19 EP disclosed
WO-2015089495-A2 COMPOSITIONS AND METHODS FOR TREATING, PREVENTING AND DIAGNOSING CANCER AND OTHER PROLIFERATIVE DISORDERS ANGIOGENEX, INC. (US) 2015-06-18 WO disclosed
CN-102236255-B Colored photosensitive resin composition, pattern forming method, color filter and manufacture thereof and display device FUJI PHOTO FILM CO LTD 2014-11-26 CN disclosed
CN-102236256-B Coloring photonasty resin composition, pattern forming method, color filter and producing method thereof and display device FUJI FILM CORP. (JP) 2014-10-08 CN disclosed
US-7927772-B2 Pigment, a dispersant, a solvent, a polymerizable compound, a photopolymerization initiator; solvents having different boiling temperatures, improving dispersion stability, film thickness uniformity, smooth pattern without any irregularities, without any residue when exposing and developing. FUJIFILM CORPORATION (JP) 2011-04-19 US disclosed
US-20080268354-A1 COLORED PHOTOPOLYMERIZABLE COMPOSITION, COLOR FILTER USING THE SAME AND METHOD OF PRODUCING COLOR FILTER FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
WO-2002017912-A1 ENDOTHELIN ANTAGONISTS ABBOTT LABORATORIES (US) 2002-03-07 WO disclosed
EP-1003740-A2 PYRROLIDINE-3-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGOISTS Abbott Laboratories (US) 2000-05-31 EP disclosed
WO-1999006397-A2 PYRROLIDINE-3-CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS ENDOTHELIN ANTAGONISTS ABBOTT LABORATORIES (US) 1999-02-11 WO disclosed
EP-0885215-A1 NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS Abbott Laboratories (US) 1998-12-23 EP disclosed
WO-1997030045-A1 NOVEL BENZO-1,3-DIOXOLYL- AND BENZOFURANYL SUBSTITUTED PYRROLIDINE DERIVATIVES AS ENDOTHELIN ANTAGONISTS ABBOTT LABORATORIES (US) 1997-08-21 WO disclosed
EP-0357409-B1 Heat-sensitive recording material FUJI PHOTO FILM CO LTD (JP) 1994-07-20 EP disclosed
EP-0357409-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1990-03-07 EP disclosed
US-4783509-A Non-thermoset thermally stable capped epoxy resin compositions THE DOW CHEMICAL COMPANY (US) 1988-11-08 US disclosed
US-4721743-A PAINTS, HIGHWAY MARKING THE DOW CHEMICAL COMPANY (US) 1988-01-26 US disclosed