Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 2/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.43 |
| ▸ | MMP1 | P03956 | 6/20 | 0.39 |
| ▸ | MMP3 | P08254 | 6/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913716 | 0.99 | PLA2G10 (0.43) | PLA2G10PLA2G5MMP1MMP3F2 | |
| SCHEMBL10913722 | 0.99 | PLA2G10 (0.43) | PLA2G10PLA2G5MMP1MMP3F2 | |
| SCHEMBL10895110 | 0.99 | PLA2G10 (0.43) | PLA2G10PLA2G5MMP1MMP3F2 | |
| SCHEMBL10914780 | 0.99 | PLA2G10 (0.43) | PLA2G10PLA2G5MMP1MMP3F2 | |
| Pidolic Acid SCHEMBL10914329 | 0.85 | PLA2G10 (0.39) | PLA2G10PLA2G5MMP1MMP3F2 | |
| Pidolic Acid SCHEMBL10914420 | 0.85 | PLA2G10 (0.39) | PLA2G10PLA2G5MMP1MMP3F2 | |
| SCHEMBL12495091 | 0.84 | MMP1 (0.52) | MMP1MMP3F2ACEDPP4 | |
| SCHEMBL12525648 | 0.84 | MMP1 (0.52) | MMP1MMP3F2ACEDPP4 | |
| SCHEMBL10954499 | 0.83 | PLA2G10 (0.43) | PLA2G10PLA2G5MMP1MMP3F2 | |
| SCHEMBL10896372 | 0.82 | PLA2G10 (0.43) | PLA2G10PLA2G5MMP1MMP3F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4757068-A | Lactams and bicyclic lactams useful as cholecystokinin antagonists | MERCK & CO., INC. (US) | 1988-07-12 | — | — | US | disclosed |