Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685760 | 0.89 | HRH3 (0.50) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL1461837 | 0.87 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL10690217 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1MAPTGAA | |
| SCHEMBL8778013 | 0.85 | MEN1 (0.47) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL31377830 | 0.83 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL29100113 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL19873004 | 0.81 | ALDH1A1 (0.62) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL21248477 | 0.81 | MEN1 (0.58) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL7487255 | 0.79 | MAPT (0.63) | ALDH1A1KMT2AMEN1HPGDMAPT | |
| SCHEMBL10684164 | 0.79 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |