Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | LAP3 | P28838 | 4/20 | 0.54 |
| ▸ | ANPEP | P15144 | 2/20 | 0.54 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.54 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690671 | 0.82 | MME (0.65) | PKMLMNALAP3ANPEPRNPEP | |
| SCHEMBL11802584 | 0.78 | MME (0.62) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL10686998 | 0.78 | LAP3 (0.51) | PKMLMNALAP3ANPEPRNPEP | |
| SCHEMBL4333811 | 0.76 | CYP3A4 (0.74) | PKMLMNALAP3ANPEPRNPEP | |
| SCHEMBL10789439 | 0.75 | CNR1 (0.71) | PKMLMNALAP3ANPEPRNPEP | |
| SCHEMBL10694799 | 0.74 | LAP3 (0.44) | PKMLMNALAP3ANPEPRNPEP | |
| SCHEMBL28325229 | 0.74 | CYP3A4 (0.67) | LAP3ANPEPRNPEPDNPEPKMT2A | |
| SCHEMBL3210919 | 0.73 | ANPEP (0.74) | PKMLMNALAP3ANPEPRNPEP | |
| SCHEMBL3210913 | 0.73 | ANPEP (0.74) | PKMLMNALAP3ANPEPRNPEP | |
| SCHEMBL7299909 | 0.73 | ANPEP (0.74) | PKMLMNALAP3ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738803-A | ENZYME INHIBITORS | ROQUES BERNARD (FR) | 1988-04-19 | — | — | US | disclosed |
| US-4618708-A | ENKEPHALINASE INHIBITOR, ANALGESICS, ANTIDEPRESSANT, ANTIDIARRHEA, OR HYPOTENSIVE AGENT | ROQUES BERNARD (FR) | 1986-10-21 | — | — | US | disclosed |