Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.74 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.74 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.74 |
| ▸ | LAP3 | P28838 | 4/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210919 | 1.00 | ANPEP (0.74) | ANPEPRNPEPDNPEPLAP3L3MBTL1 | |
| SCHEMBL3210913 | 1.00 | ANPEP (0.74) | ANPEPRNPEPDNPEPLAP3L3MBTL1 | |
| SCHEMBL21010316 | 0.87 | SLC15A1 (0.64) | ANPEPRNPEPDNPEPLAP3CYP3A4 | |
| SCHEMBL6274018 | 0.87 | ANPEP (0.57) | ANPEPRNPEPDNPEPLAP3SLC7A5 | |
| SCHEMBL4952912 | 0.87 | LAP3 (0.63) | ANPEPRNPEPDNPEPLAP3L3MBTL1 | |
| SCHEMBL20467181 | 0.87 | LAP3 (0.63) | ANPEPRNPEPDNPEPLAP3L3MBTL1 | |
| SCHEMBL20467180 | 0.87 | LAP3 (0.63) | ANPEPRNPEPDNPEPLAP3L3MBTL1 | |
| SCHEMBL18492837 | 0.85 | ANPEP (0.56) | ANPEPRNPEPDNPEPLAP3 | |
| SCHEMBL12609437 | 0.85 | ANPEP (1.00) | ANPEPRNPEPDNPEPLAP3L3MBTL1 | |
| SCHEMBL24346075 | 0.84 | MMP2 (0.60) | ANPEPRNPEPDNPEPLAP3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889712-B2 | IAP antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-11-18 | — | — | US | disclosed |
| EP-0753003-B1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-06-16 | — | — | EP | disclosed |
| US-5668128-A | INHIBITORS OF THIOL PROTEASE, PROPHYLAXIS AND TREATMENT OF BONE DISEASES, OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-16 | — | — | US | disclosed |
| EP-0753003-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995028416-A1 | AZIRIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-26 | — | — | WO | disclosed |
| US-5214056-A | Thiol protease inhibitors | JAPAN TOBACCO INC. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0460239-A1 | 1,3,2-DIOXATHIOLANE OXIDE DERIVATIVE | Japan Tobacco Inc. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4658013-A | CONTAINING ALANINE, PHENYLALANINE AND/OR TYROSINE OR METHIONINE | STERLING DRUG INC. (US) | 1987-04-14 | — | — | US | disclosed |