Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18312021 | 0.86 | LCK (0.56) | LCKFYNKDM4ENPSR1ALDH1A1 | |
| SCHEMBL1918763 | 0.86 | LCK (0.66) | LCKFYNKDM4ENPSR1ALDH1A1 | |
| SCHEMBL23173661 | 0.84 | HPGDS (0.42) | LCKFYNALDH1A1ABCB1 | |
| SCHEMBL29152481 | 0.84 | ALDH1A1 (0.53) | LCKFYNKDM4ENPSR1ALDH1A1 | |
| SCHEMBL14811899 | 0.84 | LCK (0.49) | LCKFYNKDM4ENPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4409779 | 0.84 | LCK (0.63) | LCKFYNKDM4ENPSR1ALDH1A1 | |
| SCHEMBL18309180 | 0.84 | ALDH1A1 (0.55) | LCKFYNKDM4ENPSR1ALDH1A1 | |
| SCHEMBL7015758 | 0.83 | KDM4E (0.50) | LCKFYNKDM4ENPSR1ALDH1A1 | |
| SCHEMBL25339845 | 0.82 | LCK (0.71) | LCKFYNKDM4ENPSR1ALDH1A1 | |
| SCHEMBL30448157 | 0.82 | LCK (0.71) | LCKFYNKDM4ENPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764525-A | N-1H-tetrazol-5-ylbenzamides having use as antiallergy and antiinflammatory agents | WARNER-LAMBERT COMPANY (US) | 1988-08-16 | — | — | US | disclosed |