Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11104382 | 0.89 | NT5E (0.70) | NT5EMAPTMEN1KMT2AKDM4E | |
| SCHEMBL10693431 | 0.85 | RAPGEF4 (0.59) | NT5EMAPTMEN1KMT2AKDM4E | |
| SCHEMBL10347230 | 0.84 | NT5E (0.61) | NT5EMAPTMEN1KMT2AKDM4E | |
| SCHEMBL11110261 | 0.80 | NT5E (0.69) | NT5EMAPTMEN1KMT2AKDM4E | |
| SCHEMBL10388844 | 0.80 | POLB (0.43) | NT5EMAPTMEN1KMT2ATDP1 | |
| SCHEMBL10703629 | 0.78 | NT5E (0.65) | NT5EMAPTMEN1KMT2AKDM4E | |
| SCHEMBL10708423 | 0.78 | NT5E (0.66) | NT5EMAPTMEN1KMT2AKDM4E | |
| SCHEMBL10881471 | 0.78 | NT5E (0.66) | NT5EMAPTMEN1KMT2AKDM4E | |
| SCHEMBL2032113 | 0.78 | NT5E (0.85) | NT5EMAPTMEN1KMT2AKDM4E | |
| SCHEMBL9744729 | 0.77 | NT5E (0.61) | NT5EMAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785099-A | FIBER-REACTIVE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |