Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | CASP6 | P55212 | 2/20 | 0.41 |
| ▸ | CTSV | O60911 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10632685 | 0.91 | NT5E (0.55) | NT5EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL2032113 | 0.84 | NT5E (0.85) | NT5EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL9744302 | 0.82 | MAPT (0.66) | NT5EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL9817732 | 0.80 | MAPT (0.59) | NT5EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL9877593 | 0.79 | CA2 (0.51) | NT5EMAPK1TDP1GAAPOLB | |
| SCHEMBL29597632 | 0.79 | KMT2A (0.58) | MAPTMEN1KMT2ATDP1KDM4E | |
| SCHEMBL9877922 | 0.79 | KMT2A (0.58) | MAPTMEN1KMT2ATDP1KDM4E | |
| SCHEMBL10911901 | 0.79 | RAPGEF4 (0.57) | NT5EMAPTMEN1KMT2ATDP1 | |
| SCHEMBL9878142 | 0.79 | NT5E (0.61) | NT5EMAPTMEN1KMT2AMAPK1 | |
| SCHEMBL9878203 | 0.78 | ALDH1A1 (0.50) | MAPTMEN1KMT2ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212412-B1 | POLYAZO DYES | BAYER AG (DE) | 1992-12-30 | — | — | EP | disclosed |
| US-4992589-A | Substituted phenyl hydroxyethyl sulfones, and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-12 | — | — | US | disclosed |
| EP-0171611-B1 | SUBSTITUTED PHENYLOXETHYL SULPHONES AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-23 | — | — | EP | disclosed |
| EP-0171611-A1 | Substituted phenyloxethyl sulphones and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-02-19 | — | — | EP | disclosed |