Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | NAMPT | P43490 | 9/20 | 0.51 |
| ▸ | HRAS | P01112 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | TOP1 | P11387 | 2/20 | 0.46 |
| ▸ | PRKCA | P17252 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691121 | 1.00 | HDAC1 (0.55) | HDAC1HDAC2HDAC8NAMPTHRAS | |
| Hydrochloric Acid SCHEMBL10691977 | 0.99 | HDAC1 (0.54) | HDAC1HDAC2HDAC8NAMPTHRAS | |
| Hydrochloric Acid SCHEMBL10693590 | 0.99 | HDAC1 (0.54) | HDAC1HDAC2HDAC8NAMPTHRAS | |
| SCHEMBL5447288 | 0.86 | HDAC1 (0.56) | HDAC1HDAC2HDAC8NAMPTHRAS | |
| SCHEMBL2398688 | 0.84 | HDAC1 (0.54) | HDAC1HDAC2HDAC8NAMPTHRAS | |
| SCHEMBL14355720 | 0.84 | HDAC1 (0.54) | HDAC1HDAC2HDAC8NAMPTHRAS | |
| SCHEMBL18089498 | 0.84 | HDAC1 (0.54) | HDAC1HDAC2HDAC8NAMPTHRAS | |
| SCHEMBL27282459 | 0.84 | TOP1 (0.49) | HDAC1HDAC2HDAC8HRASESR1 | |
| SCHEMBL27281179 | 0.84 | TOP1 (0.49) | HDAC1HDAC2HDAC8HRASESR1 | |
| SCHEMBL10694165 | 0.83 | HDAC1 (0.52) | HDAC1HDAC2HDAC8NAMPTHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766142-A | ANTICARCINOGENIC AGENTS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1988-08-23 | — | — | US | disclosed |