Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | FABP2 | P12104 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24230482 | 0.89 | ESR2 (0.40) | MMP2MMP3ESR2HRH3 | |
| SCHEMBL24230506 | 0.88 | ESR2 (0.39) | MMP2MMP3ESR2HRH3 | |
| SCHEMBL8935954 | 0.86 | ESR2 (0.38) | MMP2MMP3ESR2AKR1C3AKR1C2 | |
| SCHEMBL24230486 | 0.86 | ESR2 (0.36) | MMP2MMP3ESR2HRH3ALOX5AP | |
| SCHEMBL8935914 | 0.85 | ESR2 (0.37) | MMP2MMP3ESR2HRH3 | |
| SCHEMBL9019416 | 0.84 | ESR2 (0.43) | ESR2HRH3PTGS2 | |
| SCHEMBL8936039 | 0.84 | ESR2 (0.36) | MMP2MMP3ESR2 | |
| SCHEMBL20744656 | 0.84 | ESR2 (0.47) | ESR2DRD3MAPTHPGD | |
| SCHEMBL10931056 | 0.84 | ESR2 (0.47) | ESR2DRD3MAPTHPGD | |
| SCHEMBL10932075 | 0.84 | ESR2 (0.46) | ESR2DRD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0132377-B1 | COMPOUNDS CONTAINING A FLUOROBIPHENYLYL GROUP AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICE | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1988-06-29 | — | — | EP | disclosed |
| US-4696549-A | Compounds containing a fluorobiphenylyl group and their use in liquid crystal material and devices | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1987-09-29 | — | — | US | disclosed |
| US-4695131-A | FLUORINATED AROMATIC COMPOUNDS; INSTRUMENT PANELS, AUTOMOBILES | QINETIQ LIMITED (GB) | 1987-09-22 | — | — | US | disclosed |
| EP-0117631-B1 | DISUBSTITUTED ETHANES AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1987-04-29 | — | — | EP | disclosed |
| US-4594465-A | Compounds containing a fluorobiphenylyl group | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1986-06-10 | — | — | US | disclosed |
| EP-0132377-A2 | Compounds containing a fluorobiphenylyl group and their use in liquid crystal materials and device | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1985-01-30 | — | — | EP | disclosed |
| EP-0117631-A1 | Disubstituted ethanes and their use in liquid crystal materials and devices | The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) | 1984-09-05 | — | — | EP | disclosed |