Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10931056 | 1.00 | ESR2 (0.47) | ESR2NPC1CASP3RAB9ASENP8 | |
| SCHEMBL10932075 | 0.97 | ESR2 (0.46) | ESR2NPC1CASP3RAB9ASENP8 | |
| SCHEMBL11195824 | 0.93 | ESR2 (0.53) | ESR2NPC1CASP3RAB9ASENP8 | |
| SCHEMBL8448366 | 0.92 | ESR2 (0.43) | ESR2NPC1CASP3RAB9ASENP8 | |
| SCHEMBL8448364 | 0.92 | ESR2 (0.43) | ESR2NPC1CASP3RAB9ASENP8 | |
| SCHEMBL11190434 | 0.92 | ESR2 (0.54) | ESR2NPC1CASP3RAB9ASENP8 | |
| SCHEMBL10931863 | 0.91 | ESR2 (0.45) | ESR2DRD2DRD4DRD3 | |
| SCHEMBL6931071 | 0.89 | ESR2 (0.44) | ESR2DRD2DRD4DRD3 | |
| SCHEMBL8737396 | 0.89 | ESR2 (0.41) | ESR2RAB9ASMN1; SMN2GAAMAPT | |
| SCHEMBL8737394 | 0.89 | ESR2 (0.41) | ESR2RAB9ASMN1; SMN2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019034588-A1 | LIQUID-CRYSTALLINE COMPOUNDS | MERCK PATENT GMBH (DE) | 2019-02-21 | — | — | WO | disclosed |