Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24230506 | 0.92 | ESR2 (0.39) | ESR2MMP2MMP3RARBHRH3 | |
| SCHEMBL10691603 | 0.89 | MMP2 (0.43) | ESR2MMP2MMP3HRH3 | |
| SCHEMBL24230486 | 0.87 | ESR2 (0.36) | ESR2MMP2MMP3HRH3BACE1 | |
| SCHEMBL8935914 | 0.86 | ESR2 (0.37) | ESR2MMP2MMP3HRH3NPC1 | |
| SCHEMBL10930592 | 0.86 | ESR2 (0.47) | ESR2BACE1NPC1CASP3RAB9A | |
| SCHEMBL8935954 | 0.85 | ESR2 (0.38) | ESR2MMP2MMP3KDM1A | |
| SCHEMBL10927973 | 0.85 | ESR2 (0.46) | ESR2BACE1NPC1CASP3RAB9A | |
| SCHEMBL13378929 | 0.84 | ESR2 (0.39) | ESR2 | |
| SCHEMBL9019416 | 0.83 | ESR2 (0.43) | ESR2HRH3BACE1NPC1CASP3 | |
| SCHEMBL8936039 | 0.83 | ESR2 (0.36) | ESR2MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4189035-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | Merck Patent GmbH (DE) | 2023-06-07 | — | — | EP | disclosed |
| CN-116057152-A | Compound, liquid crystal medium and liquid crystal display comprising same | 默克专利股份有限公司 | 2023-05-02 | — | — | CN | disclosed |
| WO-2022023400-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | MERCK PATENT GMBH (DE) | 2022-02-03 | — | — | WO | disclosed |
| WO-2022023400-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | MERCK PATENT GMBH (DE) | 2022-02-03 | — | — | WO | disclosed |