Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 8/20 | 0.48 |
| ▸ | WNT3A | P56704 | 8/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688087 | 0.94 | CTNNB1 (0.47) | CTNNB1WNT3AHPGDTAS1R3TAS1R1 | |
| SCHEMBL7084033 | 0.92 | CTNNB1 (0.46) | CTNNB1WNT3AHPGDTAS1R3TAS1R1 | |
| SCHEMBL10693468 | 0.89 | CTNNB1 (0.47) | CTNNB1WNT3ATAS1R3TAS1R1KEAP1 | |
| SCHEMBL7762954 | 0.82 | CTNNB1 (0.47) | CTNNB1WNT3ATAS1R3TAS1R1KEAP1 | |
| SCHEMBL6975547 | 0.81 | CTNNB1 (0.45) | CTNNB1WNT3ATAS1R3TAS1R1KEAP1 | |
| SCHEMBL8139356 | 0.80 | CTNNB1 (0.51) | CTNNB1WNT3AKEAP1NFE2L2CLK1 | |
| SCHEMBL11519067 | 0.75 | DYRK1A (0.44) | CTNNB1WNT3AKEAP1NFE2L2CLK1 | |
| SCHEMBL22428725 | 0.75 | CTNNB1 (0.70) | CTNNB1WNT3AHPGDTAS1R3TAS1R1 | |
| SCHEMBL9920513 | 0.74 | CTNNB1 (0.48) | CTNNB1WNT3AHPGDTAS1R3TAS1R1 | |
| SCHEMBL27629579 | 0.71 | CTNNB1 (0.68) | CTNNB1WNT3AHPGDTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791104-A | HYPOTENSIVE, ANTILIPEMIC, ANTIHROMBOTIC, ANTIHYPOXIC AGENTS | MAGGIONI-WINTHROP S.P.A. (IT) | 1988-12-13 | — | — | US | disclosed |
| WO-1987002359-A1 | DIHYDROBENZOTHIOPHENE AND THIOCHROMANE AMINOALCOHOLS | MAGGIONI-WINTHROP S.P.A. (IT) | 1987-04-23 | — | — | WO | disclosed |