Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.45 |
| ▸ | WNT3A | P56704 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CLK1 | P49759 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693468 | 0.83 | CTNNB1 (0.47) | CTNNB1WNT3ACLK1POLBDYRK1A | |
| SCHEMBL7762954 | 0.81 | CTNNB1 (0.47) | CTNNB1WNT3ANPC1RAB9ACLK1 | |
| SCHEMBL10691617 | 0.81 | CTNNB1 (0.48) | CTNNB1WNT3ARAB9ACLK1TP53 | |
| SCHEMBL10688087 | 0.80 | CTNNB1 (0.47) | CTNNB1WNT3ARAB9ACLK1TP53 | |
| SCHEMBL8139356 | 0.79 | CTNNB1 (0.51) | CTNNB1WNT3ANPC1RAB9ACLK1 | |
| SCHEMBL7084033 | 0.79 | CTNNB1 (0.46) | CTNNB1WNT3ARAB9ACLK1TP53 | |
| SCHEMBL4848144 | 0.77 | CTNNB1 (0.56) | CTNNB1WNT3ANPC1RAB9ACLK1 | |
| SCHEMBL11242424 | 0.75 | CTNNB1 (0.54) | CTNNB1WNT3ANPC1RAB9ACLK1 | |
| SCHEMBL11519067 | 0.74 | DYRK1A (0.44) | CTNNB1WNT3ANPC1RAB9ACLK1 | |
| SCHEMBL15800506 | 0.74 | CTNNB1 (0.52) | CTNNB1WNT3ANPC1RAB9ACLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044973-B1 | Process for the dehalogenation of thiochroman and dihydrobenzothiophene derivatives | AMERICAN CYANAMID CO (US) | 2003-10-08 | — | — | EP | disclosed |
| US-6180797-B1 | MULTISTAGE REACTION AND HYDROLYSIS TO FORM HERBICIDES | AMERICAN CYANAMID CO. | 2001-01-30 | — | — | US | disclosed |
| EP-1044973-A2 | Process for the dehalogenation of thiochroman and dihydrobenzothiophene derivatives | American Cyanamid Company (US) | 2000-10-18 | — | — | EP | disclosed |
| WO-2000059898-A2 | PROCESS FOR THE DEHALOGENATION OF THIOCHROMAN AND DIHYDROBENZOTHIOPHENE DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 2000-10-12 | — | — | WO | disclosed |