Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.47 |
| ▸ | WNT3A | P56704 | 7/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691617 | 0.89 | CTNNB1 (0.48) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL10688087 | 0.88 | CTNNB1 (0.47) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL7084033 | 0.87 | CTNNB1 (0.46) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL7762954 | 0.84 | CTNNB1 (0.47) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL6975547 | 0.83 | CTNNB1 (0.45) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL8139356 | 0.82 | CTNNB1 (0.51) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL11519067 | 0.77 | DYRK1A (0.44) | CTNNB1WNT3ACLK1DYRK1ADYRK1B | |
| SCHEMBL10692370 | 0.76 | CYP4F2 (0.39) | ATMMTNR1AMTNR1BSLC6A2SLC6A4 | |
| SCHEMBL27629579 | 0.75 | CTNNB1 (0.68) | CTNNB1WNT3AATMTAS1R3TAS1R1 | |
| SCHEMBL5198324 | 0.72 | DYRK1A (0.43) | CTNNB1WNT3ACLK1DYRK1ADYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791104-A | HYPOTENSIVE, ANTILIPEMIC, ANTIHROMBOTIC, ANTIHYPOXIC AGENTS | MAGGIONI-WINTHROP S.P.A. (IT) | 1988-12-13 | — | — | US | disclosed |