Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1077104 | 0.97 | ALDH1A1 (0.33) | ALDH1A1 | |
| Bromide SCHEMBL7729199 | 0.97 | — | — | |
| SCHEMBL5732724 | 0.96 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL8468728 | 0.96 | ALDH1A1 (0.30) | ALDH1A1 | |
| Bromide SCHEMBL7722920 | 0.95 | — | — | |
| Acetonitrile SCHEMBL7724784 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL6150930 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL7183383 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL7722946 | 0.80 | — | — | |
| SCHEMBL8471987 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824888-B1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2017-01-18 | — | — | EP | disclosed |
| EP-1740626-B1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE | BASELL POLYOLEFINE GMBH (DE) | 2014-10-22 | — | — | EP | disclosed |
| US-7973114-B2 | Monocyclopentadienyl complexes | BASELL POLYOLEFINE GMBH (DE) | 2011-07-05 | — | — | US | disclosed |
| EP-1861409-B1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2011-01-19 | — | — | EP | disclosed |
| US-7834112-B2 | Method of polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2010-11-16 | — | — | US | disclosed |
| US-7795167-B2 | Cyclopentadienyl complexes of group 6 substituted by silyl halides | BASELL POLYOLEFINE GMBH (DE) | 2010-09-14 | — | — | US | disclosed |
| US-7776980-B2 | Monocyclopentadienyl complexes | BASELL POLYOLEFINE GMBH (DE) | 2010-08-17 | — | — | US | disclosed |
| EP-1572359-B1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2010-04-28 | — | — | EP | disclosed |
| US-7671148-B2 | Mixing organic transition metal compounds, hydrolyzed organoaluminum compound, and solvent, then impregnating dry porous support | BASELL POLYOLEFINE GMBH (DE) | 2010-03-02 | — | — | US | disclosed |
| US-7629464-B2 | polymerization catalyst for the polymerization of olefins; molecular weight control of polyethylene, ethylene-hexene copolymer; addition polymerization; 1-(diisopropyl(2-oxypyridine)silyl)-3-methylcyclopentadienyl)chromium dichloride | BASELL POLYOLEFINE GMBH (DE) | 2009-12-08 | — | — | US | disclosed |
| WO-2004104052-A1 | TRANSITION-METAL COMPLEXES WITH TRIDENTATE, NITROGEN-CONTAINING LIGANDS | BASELL POLYOLEFINE GMBH (DE) | 2004-12-02 | — | — | WO | disclosed |
| US-20040242880-A1 | Monocyclopentadienyl complexes comprising a condensed heterocycle | BASELL POLYOLEFINE GMBH (DE) | 2004-12-02 | — | — | US | disclosed |
| US-6780947-B1 | CHARACTERIZED IN THAT SAID LIGAND CONSISTS OF A MONO-IMINE OF 2,6-DIACYLPYRIDINE | ENICHEM S.P.A. (IT) | 2004-08-24 | — | — | US | disclosed |
| WO-2004056482-A1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2004-07-08 | — | — | WO | disclosed |
| WO-2004056481-A1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2004-07-08 | — | — | WO | disclosed |
| WO-2004020479-A2 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004018489-A1 | MONOCYCLOPENTADIENYL COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2004-03-04 | — | — | WO | disclosed |
| EP-0946609-B1 | POLYMERIZATION OF ETHYLENE WITH SPECIFIC IRON OR COBALT COMPLEXES, NOVEL PYRIDINEBIS(IMINES) AND NOVEL COMPLEXES OF PYRIDINEBIS(IMINES) WITH IRON AND COBALT | DU PONT (US) | 2002-02-27 | — | — | EP | disclosed |
| EP-1127897-A2 | Catalyst composition comprising specific iron or cobalt complexes and process for the oligomerization or polymerization of ethylene therewith | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-08-29 | — | — | EP | disclosed |
| WO-2001010875-A1 | METAL COMPLEXES COMPRISING A 2,6-DIACYLPYRIDINE-LIGAND AND THEIR USE IN THE POLYMERIZATION OF ETHYLENE | ENICHEM S.P.A. (IT) | 2001-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242880-A1 | Monocyclopentadienyl complexes comprising a condensed heterocycle | MCM4, MCM3, CCNC | ALDH1A1 2650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.