Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691712 | 0.87 | SRD5A2 (0.41) | HPGDRAB9ANPC1MIFSMN1; SMN2 | |
| SCHEMBL8787024 | 0.80 | PDE3B (0.45) | ALDH1A1HPGDRAB9ANPC1MEN1 | |
| SCHEMBL28373618 | 0.78 | CA12 (0.60) | ALDH1A1HPGDRAB9ANPC1MEN1 | |
| SCHEMBL9437730 | 0.77 | PTPN1 (0.47) | ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL10695779 | 0.74 | ALDH1A1 (0.49) | ALDH1A1HPGDRAB9ANPC1MEN1 | |
| SCHEMBL10926839 | 0.73 | CA9 (0.56) | ALDH1A1HPGDRAB9ANPC1MEN1 | |
| SCHEMBL6938 | 0.71 | PDE3B (0.51) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL30030322 | 0.71 | PDE3B (0.51) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL9718973 | 0.71 | MEN1 (0.81) | ALDH1A1HPGDRAB9ANPC1MEN1 | |
| Hydrochloric Acid SCHEMBL7394595 | 0.70 | PDE3B (0.50) | ALDH1A1HPGDRAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |