Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691670 | 0.87 | ALDH1A1 (0.48) | SRD5A2MAPK1SMN1; SMN2CA12CA9 | |
| SCHEMBL8787024 | 0.79 | PDE3B (0.45) | PDE3BPDE3ACA12CA9MAPT | |
| SCHEMBL9437730 | 0.75 | PTPN1 (0.47) | PDE3BPDE3AMAPTPOLB | |
| SCHEMBL10693571 | 0.75 | TTR (0.45) | SRD5A2MAPK1SMN1; SMN2TTRCA12 | |
| SCHEMBL5518679 | 0.72 | SRD5A2 (0.61) | SRD5A2MAPK1CNR2SMN1; SMN2HTT | |
| SCHEMBL10926839 | 0.72 | CA9 (0.56) | PDE3BPDE3ACA12CA9MAPT | |
| SCHEMBL3922666 | 0.72 | PDE3B (0.58) | MAPK1PDE3BPDE3ASMN1; SMN2CA12 | |
| SCHEMBL9475353 | 0.70 | SRD5A2 (0.59) | SRD5A2MAPK1CNR2SMN1; SMN2HTT | |
| SCHEMBL8967726 | 0.69 | SRD5A2 (0.57) | SRD5A2MAPK1CNR2SMN1; SMN2HTT | |
| SCHEMBL9471701 | 0.68 | TTR (0.57) | SRD5A2MAPK1CNR2SMN1; SMN2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |