Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 11/20 | 0.90 |
| ▸ | KDM4A | O75164 | 3/20 | 0.79 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.79 |
| ▸ | KDM5A | P29375 | 1/20 | 0.79 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.79 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833833 | 0.95 | ALOX5 (1.00) | ALOX5KDM4AKDM4CKDM5APHF8 | |
| SCHEMBL1271129 | 0.86 | ALOX5 (1.00) | ALOX5KDM4AKDM4CKDM5APHF8 | |
| SCHEMBL10695268 | 0.84 | ALOX5 (1.00) | ALOX5KDM4AKDM4CKDM5APHF8 | |
| SCHEMBL3049698 | 0.84 | ALOX5 (0.68) | ALOX5KDM4AKDM4CKDM5APHF8 | |
| SCHEMBL10692283 | 0.83 | ALOX5 (0.79) | ALOX5KDM4AKDM4CKDM5APHF8 | |
| SCHEMBL28147120 | 0.83 | ALOX5 (0.72) | ALOX5KDM4AKDM4CKDM5APHF8 | |
| SCHEMBL16792012 | 0.82 | KDM4A (0.68) | ALOX5KDM4AKDM4CKDM5APHF8 | |
| SCHEMBL10697496 | 0.82 | ALOX5 (1.00) | ALOX5KDM4AKDM4CKDM5APHF8 | |
| SCHEMBL9834381 | 0.82 | ALOX5 (0.77) | ALOX5KDM4AKDM4CKDM5APHF8 | |
| SCHEMBL17117230 | 0.81 | ALOX5 (0.71) | ALOX5KDM4AKDM4CKDM5APHF8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | claimed |
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |