Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 13/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | KDM4A | O75164 | 1/20 | 0.57 |
| ▸ | KDM5A | P29375 | 1/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.57 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.57 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.57 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.56 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.56 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.56 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9833833 | 0.87 | ALOX5 (1.00) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL10695970 | 0.86 | ALOX5 (1.00) | ALOX5ALDH1A1NPC1RAB9A | |
| SCHEMBL7448130 | 0.83 | ALOX5 (0.70) | ALOX5ALDH1A1KDM4AKDM5AKDM4C | |
| SCHEMBL10691673 | 0.82 | ALOX5 (0.90) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL31329298 | 0.81 | ALOX5 (0.68) | ALOX5ALDH1A1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL10691859 | 0.81 | ALOX5 (1.00) | ALOX5ALDH1A1 | |
| SCHEMBL31329279 | 0.80 | ALOX5 (0.69) | ALOX5ALDH1A1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL3049698 | 0.80 | ALOX5 (0.68) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL9834381 | 0.79 | ALOX5 (0.77) | ALOX5KDM4AKDM5AKDM4CPHF8 | |
| SCHEMBL31329297 | 0.78 | ALOX5 (0.82) | ALOX5ALDH1A1PLAAT3PLAAT5PLAAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | claimed |
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |