SCHEMBL10691685

SCHEMBL10691685

N#CC(CO)(CO)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.44
ALDH1A1 P00352 4/20 0.42
POLB P06746 1/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
MMP14 P50281 1/20 0.41
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CES1 P23141 1/20 0.40
CA5A P35218 1/20 0.40
CA9 Q16790 1/20 0.40
LOXL2 Q9Y4K0 1/20 0.39
KDM4E B2RXH2 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CYP2C19 P33261 1/20 0.39
GSK3B P49841 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10694828 0.83 CA1 (0.44) TSHRALDH1A1POLBMAPK1TDP1
SCHEMBL2817150 0.83 ALDH1A1 (0.49) ALDH1A1POLBMAPK1MAPTCA1
SCHEMBL28680251 0.78 CYP1A2 (0.46) ALDH1A1MAPTMEN1KMT2ACES1
SCHEMBL10943065 0.76 TSHR (0.52) TSHRALDH1A1POLBMAPK1TDP1
SCHEMBL8749758 0.75 ALDH1A1 (0.46) ALDH1A1POLBMAPK1TDP1MAPT
SCHEMBL8666047 0.75 ALDH1A1 (0.46) ALDH1A1POLBMAPK1TDP1MAPT
SCHEMBL2873973 0.75 MAPT (0.51) ALDH1A1POLBMAPK1MAPTMEN1
SCHEMBL12982916 0.74 TSHR (0.50) TSHRALDH1A1POLBTDP1CA1
SCHEMBL28455171 0.74 HSD17B10 (0.48) ALDH1A1POLBMAPK1TDP1MAPT
SCHEMBL7865942 0.74 HSD11B1 (0.49) ALDH1A1POLBMAPK1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0261073-A2 Insecticidal and acaricidal alkane and alkoxy alkane derivatives SCHERING AKTIENGESELLSCHAFT (DE) 1988-03-23 EP disclosed
CN-87105707-A Desinsection and the alkane and the alkoxy derivatives alkane that kill mite 1988-03-09 CN disclosed