SCHEMBL10691748

SCHEMBL10691748

COc1cc(C)ccc1C(=O)c1ccc(N(C)C)cc1C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
TSHR P16473 1/20 0.51
CYP2C19 P33261 1/20 0.51
PLAU P00749 1/20 0.47
LTC4S Q16873 3/20 0.44
ALDH1A1 P00352 3/20 0.43
MAPT P10636 4/20 0.42
MAPK1 P28482 2/20 0.42
HSD17B10 Q99714 1/20 0.42
CDC25B P30305 1/20 0.42
HTT P42858 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
USP2 O75604 1/20 0.41
TLR9 Q9NR96 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17202768 0.92 MEN1 (0.59) LMNAMEN1KMT2ACYP1A2CYP3A4
SCHEMBL30108715 0.87 ALDH1A1 (0.51) LMNAALDH1A1MAPTHSD17B10CDC25B
SCHEMBL9312599 0.81 MEN1 (0.69) LMNAMEN1KMT2ACYP1A2CYP3A4
SCHEMBL30108835 0.81 ALDH1A1 (0.51) LMNAPLAUALDH1A1MAPTHSD17B10
SCHEMBL27908567 0.81 LMNA (0.59) LMNAMEN1KMT2ACYP1A2CYP3A4
SCHEMBL18138756 0.81 TUBB1 (0.51) LMNAMEN1KMT2ACYP1A2CYP3A4
SCHEMBL11437867 0.79 CSNK2A1 (0.44) LMNAMEN1KMT2ATSHRLTC4S
SCHEMBL365917 0.79 ALDH1A1 (0.65) PLAUALDH1A1MAPTHSD17B10HTT
SCHEMBL17202194 0.79 MEN1 (0.55) LMNAMEN1KMT2ACYP1A2CYP3A4
SCHEMBL10605623 0.79 AKR1C3 (0.58) LMNAMEN1KMT2ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9938232-B2 LED photoinitiators SUN CHEMICAL CORPORATION (US) 2018-04-10 US claimed
US-20170044093-A1 LED PHOTOINITIATORS SUN CHEMICAL CORPORATION (US) 2017-02-16 US claimed
EP-3134443-B1 LED PHOTOINITIATORS SUN CHEMICAL CORP (US) 2019-10-30 EP disclosed
US-9938232-B2 LED photoinitiators SUN CHEMICAL CORPORATION (US) 2018-04-10 US disclosed
EP-3134443-A1 LED PHOTOINITIATORS Sun Chemical Corporation (US) 2017-03-01 EP disclosed
US-20170044093-A1 LED PHOTOINITIATORS SUN CHEMICAL CORPORATION (US) 2017-02-16 US disclosed
WO-2015164208-A1 LED PHOTOINITIATORS SUN CHEMICAL CORPORATION (US) 2015-10-29 WO disclosed
US-4748148-A Recording system utilizing phthalide derivatives as colorless chromogenic material NEW OJI PAPER CO., LTD. (JP) 1988-05-31 US disclosed
US-4641160-A Recording system utilizing phthalide derivatives as colorless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1987-02-03 US disclosed
EP-0127203-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-12-05 EP disclosed
EP-0062544-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1982-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044093-A1 LED PHOTOINITIATORS CCNA1, CYBA, H1-0 LMNA 252/4885MEN1 1655/4885KMT2A 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.