Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BMP1 | P13497 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688673 | 0.86 | MEN1 (0.37) | LMNAKDM4EALDH1A1USP2MMP9 | |
| SCHEMBL12406856 | 0.85 | CYP1A2 (0.38) | LMNAKDM4EALDH1A1USP2MMP9 | |
| SCHEMBL1546590 | 0.85 | CYP1A2 (0.38) | LMNAKDM4EALDH1A1USP2MMP9 | |
| SCHEMBL23182529 | 0.80 | GABBR2 (0.42) | LMNAKDM4EALDH1A1USP2MMP9 | |
| SCHEMBL11852043 | 0.76 | GABBR2 (0.40) | LMNAMMP9TSHRSMN1; SMN2 | |
| SCHEMBL18740520 | 0.75 | APLNR (0.44) | ALDH1A1TSHRACHEL3MBTL1CA12 | |
| SCHEMBL11027775 | 0.74 | IDO1 (0.55) | LMNAKDM4EIDO1CNR2BCHE | |
| SCHEMBL10832161 | 0.74 | GABBR2 (0.38) | CNR2 | |
| SCHEMBL11854719 | 0.74 | NR1I2 (0.40) | LMNAALDH1A1MMP9CNR2SMN1; SMN2 | |
| SCHEMBL13210865 | 0.73 | NR1I2 (0.39) | LMNAKDM4EALDH1A1USP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253501-A2 | N-disubstituted cycloalkylmethyl amines useful as fungicides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-01-20 | — | — | EP | disclosed |