Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8432471 | 0.88 | MME (0.79) | MMEMMP8 | |
| SCHEMBL10687449 | 0.85 | MME (0.74) | MMEMMP8 | |
| SCHEMBL10967607 | 0.84 | MMP8 (0.76) | MMEMMP8 | |
| SCHEMBL4909594 | 0.83 | MMP8 (0.72) | MMEMMP8 | |
| SCHEMBL10692309 | 0.82 | MME (0.69) | MMEMMP8 | |
| SCHEMBL7357043 | 0.80 | MMP8 (1.00) | MMEMMP8 | |
| SCHEMBL10690671 | 0.80 | MME (0.65) | MMEMMP8 | |
| SCHEMBL10447979 | 0.80 | MME (0.81) | MME | |
| SCHEMBL11805463 | 0.78 | ACE (0.69) | MME | |
| SCHEMBL7358056 | 0.78 | MMP8 (0.89) | MMEMMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0075896-B1 | PHARMACEUTICAL AMIDES, AND PREPARATION, FORMULATIONS AND USE THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-02-26 | — | — | EP | claimed |
| EP-0075896-A2 | Pharmaceutical amides, and preparation, formulations and use thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-04-06 | — | — | EP | claimed |
| US-4738803-A | ENZYME INHIBITORS | ROQUES BERNARD (FR) | 1988-04-19 | — | — | US | disclosed |
| US-4618708-A | ENKEPHALINASE INHIBITOR, ANALGESICS, ANTIDEPRESSANT, ANTIDIARRHEA, OR HYPOTENSIVE AGENT | ROQUES BERNARD (FR) | 1986-10-21 | — | — | US | disclosed |