Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 8/20 | 0.81 |
| ▸ | ACE | P12821 | 4/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.81 |
| ▸ | HPGD | P15428 | 1/20 | 0.81 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 1/20 | 0.81 |
| ▸ | ECE1 | P42892 | 1/20 | 0.81 |
| ▸ | BLM | P54132 | 1/20 | 0.81 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103054 | 0.91 | MME (0.74) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL825762 | 0.91 | MME (0.74) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL9622300 | 0.90 | MME (0.72) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL9622302 | 0.90 | MME (0.72) | MMEACEALDH1A1HPGDMAPK1 | |
| (S)-Thiorphan SCHEMBL49662 | 0.90 | MME (1.00) | MMEACEALDH1A1HPGDMAPK1 | |
| Thiorphan SCHEMBL401174 | 0.90 | MME (1.00) | MMEACEALDH1A1HPGDMAPK1 | |
| (R)-Thiorphan SCHEMBL7312756 | 0.90 | MME (1.00) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL10691553 | 0.89 | MME (0.70) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL19437143 | 0.89 | MME (0.70) | MMEACEALDH1A1HPGDMAPK1 | |
| SCHEMBL7325851 | 0.86 | MME (1.00) | MMEACEALDH1A1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0386611-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1990-09-12 | — | — | EP | disclosed |