Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10428930 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2C19L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL10691329 | 1.00 | CYP1A2 (0.56) | CYP1A2CYP2C19L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL4871149 | 0.85 | CYP1A2 (0.76) | CYP1A2CYP2C19L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL10995722 | 0.84 | CYP1A2 (0.51) | CYP1A2CYP2C19SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL10428684 | 0.82 | L3MBTL1 (0.55) | CYP1A2CYP2C19L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL10694480 | 0.80 | L3MBTL1 (0.69) | CYP1A2CYP2C19L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL10694485 | 0.80 | L3MBTL1 (0.69) | CYP1A2CYP2C19L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL7107465 | 0.78 | MAPT (0.68) | CYP1A2CYP2C19L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL11184434 | 0.78 | MAPT (0.68) | CYP1A2CYP2C19L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL7107470 | 0.78 | MAPT (0.68) | CYP1A2CYP2C19L3MBTL1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4782162-A | Novel intermediates for the synthesis of cephalosporins | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-01 | — | — | US | disclosed |
| EP-0161617-A2 | Intermediates and process for the preparation of intermediates in the synthesis of cephalosporins | BAYER AG (DE) | 1985-11-21 | — | — | EP | disclosed |