Sugi Predict

Sugi Predict / Compounds / SCHEMBL7107470

SCHEMBL7107470

SCHEMBL7107470

CC=C(C(=O)OCC)c1csc(N)n1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.68
▸ RAB9A P51151 5/20 0.68
▸ ALDH1A1 P00352 4/20 0.68
▸ NPC1 O15118 4/20 0.68
▸ MEN1 O00255 3/20 0.68
▸ KMT2A Q03164 3/20 0.68
▸ TDP1 Q9NUW8 2/20 0.45
▸ L3MBTL1 Q9Y468 2/20 0.45
▸ MAPK1 P28482 2/20 0.45
▸ LMNA P02545 1/20 0.45
▸ SMN1; SMN2 Q16637 3/20 0.43
▸ GAA P10253 2/20 0.43
▸ PKM P14618 2/20 0.42
▸ HTT P42858 2/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ CYP1A2 P05177 1/20 0.42
▸ CYP2C19 P33261 1/20 0.42
▸ TSHR P16473 2/20 0.41
▸ POLB P06746 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11184434 1.00 MAPT (0.68) MAPTRAB9AALDH1A1NPC1MEN1
SCHEMBL7107465 1.00 MAPT (0.68) MAPTRAB9AALDH1A1NPC1MEN1
SCHEMBL7099452 0.89 ALDH1A1 (0.61) MAPTRAB9AALDH1A1NPC1MEN1
SCHEMBL27508426 0.89 ALDH1A1 (0.61) MAPTRAB9AALDH1A1NPC1MEN1
SCHEMBL7107222 0.89 MAPT (0.57) MAPTRAB9AALDH1A1NPC1MEN1
SCHEMBL10922760 0.89 MAPT (0.61) MAPTRAB9AALDH1A1NPC1MEN1
SCHEMBL7099455 0.89 ALDH1A1 (0.61) MAPTRAB9AALDH1A1NPC1MEN1
SCHEMBL7107220 0.89 MAPT (0.57) MAPTRAB9AALDH1A1NPC1MEN1
SCHEMBL10921142 0.89 MAPT (0.61) MAPTRAB9AALDH1A1NPC1MEN1
SCHEMBL7100527 0.86 MAPT (0.58) MAPTRAB9AALDH1A1NPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1000939-B1 Producing z-isomer of hydrogen bromide salt of 2-aminothiazole derivative SUMITOMO CHEMICAL CO (JP) 2003-09-17 — — EP disclosed
US-6403572-B1 REACTING ACID SALT OF A 2-AMINOTHIAZOLE COMPOUND WITH INORGANIC ACID SUMITOMO CHEMICAL CO., LTD. (JP) 2002-06-11 — — US disclosed
US-20020058818-A1 Producing Z-isomer of hydrogen bromide salt of 2-aminothiazole derivative SUMITOMO CHEMICAL CO., LTD. 2002-05-16 — — US disclosed
US-6340763-B1 SALT FORMATION AND CRYSTALLIZATION, REACTION OF HALOGENATED COMPOUND AND THIOUREA COMPOUND SUMITOMO CHEMICAL CO., LTD. (JP) 2002-01-22 — — US disclosed
EP-1000939-A1 Producing z-isomer of hydrogen bromide salt of 2-aminothiazole derivative SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-05-17 — — EP disclosed
US-4416880-A β-Lactam antibiotics and compositions containing the same BAYER AKTIENGESELLSCHAFT (DE) 1983-11-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058818-A1 Producing Z-isomer of hydrogen bromide salt of 2-aminothiazole derivative ZYX, H1-0, HAO2 MAPT 1584/4885RAB9A 540/4885ALDH1A1 2333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.