SCHEMBL10691898

SCHEMBL10691898

COc1ccc(C2(C=C(c3ccc(N(C)C)cc3)c3ccc(N(C)C)cc3)OC(=O)c3cc(N(C)C)ccc32)c(OC)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
CYP3A4 P08684 2/20 0.45
LMNA P02545 2/20 0.45
CYP1A2 P05177 1/20 0.45
TSHR P16473 1/20 0.45
CYP2C19 P33261 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
HIF1A Q16665 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MAPT P10636 4/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
USP2 O75604 1/20 0.41
MAPK1 P28482 1/20 0.41
TLR9 Q9NR96 1/20 0.41
MAOB P27338 3/20 0.37
MAOA P21397 1/20 0.37
TUBB1 Q9H4B7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10606214 0.88 CYP3A4 (0.51) MEN1KMT2ACYP3A4LMNACYP1A2
SCHEMBL10691280 0.86 CYP3A4 (0.49) MEN1KMT2ACYP3A4LMNACYP1A2
SCHEMBL338334 0.82 ALDH1A1 (0.59) MEN1KMT2ACYP3A4LMNACYP1A2
SCHEMBL10604255 0.80 CYP3A4 (0.42) MEN1KMT2ACYP3A4LMNACYP1A2
SCHEMBL10604959 0.78 ALDH1A1 (0.54) MEN1KMT2ACYP3A4TSHRTDP1
SCHEMBL28910547 0.77 ALDH1A1 (0.53) MEN1KMT2ACYP3A4LMNATDP1
SCHEMBL9313469 0.77 MEN1 (0.42) MEN1KMT2ACYP3A4LMNACYP1A2
SCHEMBL10692785 0.77 CYP3A4 (0.69) MEN1KMT2ACYP3A4LMNACYP1A2
SCHEMBL10604581 0.77 ALDH1A1 (0.41) MEN1KMT2ACYP3A4LMNACYP1A2
SCHEMBL10604586 0.77 ALDH1A1 (0.41) MEN1KMT2ACYP3A4LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4748148-A Recording system utilizing phthalide derivatives as colorless chromogenic material NEW OJI PAPER CO., LTD. (JP) 1988-05-31 US disclosed
US-4641160-A Recording system utilizing phthalide derivatives as colorless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1987-02-03 US disclosed
EP-0127203-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-12-05 EP disclosed