SCHEMBL10691280

SCHEMBL10691280

COc1ccc(C2(C=C(c3ccc(N(C)C)cc3)c3ccc(N(C)C)cc3)OC(=O)c3cc(N(C)C)ccc32)cc1OC

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.49
ALDH1A1 P00352 1/20 0.49
HPGD P15428 1/20 0.49
HIF1A Q16665 1/20 0.49
HSD17B10 Q99714 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37
NQO2 P16083 1/20 0.37
LMNA P02545 3/20 0.35
MAPT P10636 2/20 0.35
HTT P42858 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
ABCB1 P08183 2/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL338334 0.88 ALDH1A1 (0.59) CYP3A4ALDH1A1HPGDHIF1AHSD17B10
SCHEMBL10606214 0.88 CYP3A4 (0.51) CYP3A4ALDH1A1HPGDHIF1AHSD17B10
SCHEMBL10691898 0.86 MEN1 (0.45) CYP3A4ALDH1A1HPGDHIF1AHSD17B10
SCHEMBL10604959 0.84 ALDH1A1 (0.54) CYP3A4ALDH1A1HPGDHIF1AHSD17B10
SCHEMBL28910547 0.83 ALDH1A1 (0.53) CYP3A4ALDH1A1HPGDHIF1AHSD17B10
SCHEMBL10604255 0.80 CYP3A4 (0.42) CYP3A4ALDH1A1HPGDHIF1AHSD17B10
SCHEMBL339310 0.78 TDP1 (0.44) CYP3A4ALDH1A1HPGDHIF1AHSD17B10
SCHEMBL9314487 0.77 CYP3A4 (0.46) CYP3A4ALDH1A1HPGDHIF1AHSD17B10
SCHEMBL10604586 0.77 ALDH1A1 (0.41) CYP3A4ALDH1A1HPGDHIF1AHSD17B10
SCHEMBL10604581 0.77 ALDH1A1 (0.41) CYP3A4ALDH1A1HPGDHIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4748148-A Recording system utilizing phthalide derivatives as colorless chromogenic material NEW OJI PAPER CO., LTD. (JP) 1988-05-31 US disclosed
US-4641160-A Recording system utilizing phthalide derivatives as colorless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1987-02-03 US disclosed
EP-0127203-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-12-05 EP disclosed
EP-0062544-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1982-10-13 EP disclosed