Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 4/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694125 | 0.91 | KDM4E (0.47) | ALDH1A1KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL10344390 | 0.90 | ALDH1A1 (0.56) | ALDH1A1KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL10344312 | 0.84 | MAOB (0.46) | ALDH1A1KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL10592936 | 0.82 | ALDH1A1 (0.66) | ALDH1A1KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL10695261 | 0.82 | BRD4 (0.50) | ALDH1A1KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL10344382 | 0.79 | PPARG (0.60) | — | |
| SCHEMBL10344392 | 0.79 | PPARG (0.60) | — | |
| SCHEMBL10344547 | 0.79 | PPARG (0.60) | — | |
| SCHEMBL10344548 | 0.78 | AKT1 (0.41) | ALDH1A1KDM4ENPC1MAPK1RAB9A | |
| SCHEMBL10693383 | 0.76 | LTB4R (0.40) | ALDH1A1KDM4EGAAHPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261254-A1 | 3,4-Dihydro-4-oxo-2H-1-benzopyranyloxy alkanoic acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-03-30 | — | — | EP | disclosed |
| US-4650812-A | ANTIALLERGY | HOFFMANN-LA ROCHE INC. (US) | 1987-03-17 | — | — | US | disclosed |