Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686365 | 0.92 | KCNH2 (0.61) | KCNH2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10674269 | 0.86 | ALDH1A1 (0.50) | KCNH2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL10685351 | 0.85 | KCNH2 (0.45) | KCNH2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10863591 | 0.85 | KCNH2 (0.45) | KCNH2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11299259 | 0.80 | ALDH1A1 (0.54) | KMT2AALDH1A1MAPK1HTTLMNA | |
| SCHEMBL11255036 | 0.79 | KCNH2 (0.41) | KCNH2MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16407272 | 0.77 | ALDH1A1 (0.51) | KCNH2KMT2AALDH1A1MAPK1HTT | |
| SCHEMBL2686608 | 0.74 | ALDH1A1 (0.49) | KCNH2ALDH1A1MAPK1HTTLMNA | |
| SCHEMBL9547886 | 0.74 | ALDH1A1 (0.56) | KMT2AALDH1A1MAPK1HTTLMNA | |
| SCHEMBL11256592 | 0.73 | KCNH2 (0.37) | KCNH2MEN1KMT2ASMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728659-A | ANTICOAGULANTS | SS PHARMACEUTICAL CO., LTD. (JP) | 1988-03-01 | — | — | US | disclosed |
| EP-0169400-A1 | Aminomethyl derivatives and preparation process thereof as well as platelet aggregation inhibitors containing same | SS PHARMACEUTICAL CO., LTD. (JP) | 1986-01-29 | — | — | EP | disclosed |
| US-4418079-A | Conjugated ketone compounds in preventing platelet thrombosis | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-11-29 | — | — | US | disclosed |