Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.47 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16407272 | 0.84 | ALDH1A1 (0.51) | ALDH1A1MAPK1HTTLMNATSHR | |
| SCHEMBL25993084 | 0.82 | ESR1 (0.47) | ALDH1A1LMNATSHRKDM4EHIF1A | |
| SCHEMBL2686608 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPK1HTTLMNATSHR | |
| SCHEMBL9547886 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPK1HTTLMNATSHR | |
| SCHEMBL29007624 | 0.80 | AOC3 (0.41) | ALDH1A1MAPK1HTTLMNATSHR | |
| SCHEMBL9243871 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPK1HTTLMNATSHR | |
| SCHEMBL10691972 | 0.80 | KCNH2 (0.54) | ALDH1A1MAPK1HTTLMNATSHR | |
| SCHEMBL9547891 | 0.79 | TSHR (0.64) | ALDH1A1MAPK1HTTLMNATSHR | |
| SCHEMBL28504713 | 0.79 | ALDH1A1 (0.54) | ALDH1A1MAPK1HTTLMNATSHR | |
| SCHEMBL10674269 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPK1HTTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4273944-A | Method for selective preparation of cis isomers of ethylenically unsaturated compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1981-06-16 | — | — | US | claimed |
| US-8269047-B2 | Synthesis of alpha-halo enones and enals | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA, RENO (US) | 2012-09-18 | — | — | US | disclosed |
| US-20110021806-A1 | SYNTHESIS OF ALPHA-HALO ENONES AND ENALS | Board of Regents of the Nevada System of Higher Education, on behalf of the Univ of Nevada, Reno (US) | 2011-01-27 | — | — | US | disclosed |
| EP-0011439-B1 | METHOD FOR SELECTIVE PREPARATION OF CIS ISOMERS OF ETHYLENICALLY UNSATURATED COMPOUNDS | Shin-Etsu Chemical Co., Ltd. (JP) | 1982-05-05 | — | — | EP | disclosed |
| US-4273944-A | Method for selective preparation of cis isomers of ethylenically unsaturated compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1981-06-16 | — | — | US | disclosed |
| EP-0011439-A1 | Method for selective preparation of cis isomers of ethylenically unsaturated compounds | Shin-Etsu Chemical Co., Ltd. (JP) | 1980-05-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021806-A1 | SYNTHESIS OF ALPHA-HALO ENONES AND ENALS | ADH1C, ADH1A, AP1S1 | ALDH1A1 322/4885MAPK1 3081/4885HTT 1267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.