Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TKT | P29401 | 2/20 | 0.33 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10691595 | 0.98 | LMNA (0.39) | LMNACYP1A2TSHRHTTPOLB | |
| SCHEMBL10688382 | 0.75 | CYP1A2 (0.64) | LMNACYP1A2TSHRHTTNFKB1 | |
| SCHEMBL17677224 | 0.75 | LMNA (0.43) | LMNACYP1A2TSHRNFKB1BLM | |
| SCHEMBL8626075 | 0.75 | LMNA (0.43) | LMNACYP1A2TSHRNFKB1BLM | |
| SCHEMBL4832458 | 0.75 | LMNA (0.43) | LMNACYP1A2TSHRNFKB1BLM | |
| Hydrochloric Acid SCHEMBL10954513 | 0.73 | LMNA (0.42) | LMNACYP1A2TSHRNFKB1BLM | |
| Hydrochloric Acid SCHEMBL10687884 | 0.72 | MAPT (0.45) | LMNAHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10691231 | 0.71 | HPGD (0.36) | TSHRHTTALDH1A1 | |
| SCHEMBL28146377 | 0.69 | RET (0.39) | CYP1A2HTTPOLB | |
| SCHEMBL9901402 | 0.67 | NPC1 (0.46) | CYP1A2HTTPOLBBLMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4794182-A | 2-Alkyl-4-amino-5-aminomethylpyrimidines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-27 | — | — | US | disclosed |