Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692894 | 0.79 | IMPDH2 (0.30) | — | |
| SCHEMBL11306419 | 0.73 | DHFR (0.42) | — | |
| SCHEMBL10714315 | 0.72 | DHFR (0.39) | — | |
| SCHEMBL10691982 | 0.71 | LMNA (0.40) | TSHRALDH1A1HTT | |
| SCHEMBL11007177 | 0.71 | DHFR (0.36) | — | |
| SCHEMBL1572808 | 0.70 | DHFR (0.37) | — | |
| Hydrochloric Acid SCHEMBL10691595 | 0.70 | LMNA (0.39) | TSHRALDH1A1HTT | |
| SCHEMBL11839014 | 0.69 | DHFR (0.36) | — | |
| SCHEMBL10998624 | 0.68 | IMPDH2 (0.35) | — | |
| SCHEMBL10696235 | 0.68 | TP53 (0.57) | HPGDTSHRMAPK1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4794182-A | 2-Alkyl-4-amino-5-aminomethylpyrimidines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-12-27 | — | — | US | disclosed |