Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.73 |
| ▸ | DRD4 | P21917 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.73 |
| ▸ | DRD3 | P35462 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10365114 | 0.91 | MEN1 (0.61) | DRD2DRD4HTR2ADRD3MEN1 | |
| Mespiperone SCHEMBL1901596 | 0.85 | DRD2 (1.00) | DRD2DRD4HTR2ADRD3MEN1 | |
| SCHEMBL31010888 | 0.85 | DRD2 (0.74) | DRD2DRD4HTR2ADRD3MEN1 | |
| Mespiperone SCHEMBL10733631 | 0.84 | DRD2 (0.98) | DRD2DRD4HTR2ADRD3MEN1 | |
| SCHEMBL12239761 | 0.76 | DRD2 (0.70) | DRD2DRD4HTR2ADRD3MEN1 | |
| SCHEMBL11375015 | 0.76 | DRD2 (0.77) | DRD2DRD4HTR2ADRD3MEN1 | |
| SCHEMBL11499003 | 0.75 | DRD2 (0.76) | DRD2DRD4HTR2ADRD3MEN1 | |
| Hydrochloric Acid SCHEMBL10735573 | 0.75 | DRD2 (0.81) | DRD2DRD4HTR2ADRD3MEN1 | |
| SCHEMBL29462918 | 0.74 | DRD2 (0.79) | DRD2DRD4HTR2ADRD3MEN1 | |
| SCHEMBL318990 | 0.74 | DRD2 (0.75) | DRD2DRD4HTR2ADRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739060-A | Radioactive and non-radioactive iodobutyrophenone derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0213883-A1 | Novel radioactive and non-radioactive iodobutyrophenone derivative and processes for the preparation thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-03-11 | — | — | EP | disclosed |