Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 7/20 | 0.62 |
| ▸ | PRMT6 | Q96LA8 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5967401 | 0.98 | CARM1 (0.64) | CARM1PRMT6HPGDGAAHDAC8 | |
| SCHEMBL4680706 | 0.86 | MAPK1 (0.55) | CARM1PRMT6HPGDGAAL3MBTL1 | |
| SCHEMBL4676331 | 0.86 | MAPK1 (0.55) | CARM1PRMT6HPGDGAAL3MBTL1 | |
| SCHEMBL12375175 | 0.86 | HPGD (0.65) | HPGDGAAL3MBTL1MAPK1TSHR | |
| SCHEMBL24648968 | 0.84 | CARM1 (0.56) | CARM1PRMT6MAPK1LMNA | |
| SCHEMBL9200501 | 0.84 | CARM1 (0.56) | CARM1PRMT6 | |
| SCHEMBL9199910 | 0.84 | CARM1 (0.56) | CARM1PRMT6 | |
| SCHEMBL30956341 | 0.84 | MEN1 (0.59) | CARM1PRMT6HPGDGAAHDAC8 | |
| SCHEMBL10688879 | 0.84 | ANPEP (0.59) | CARM1PRMT6HPGDGAAL3MBTL1 | |
| SCHEMBL7955857 | 0.83 | HPGD (0.54) | CARM1PRMT6HPGDGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738803-A | ENZYME INHIBITORS | ROQUES BERNARD (FR) | 1988-04-19 | — | — | US | disclosed |
| US-4618708-A | ENKEPHALINASE INHIBITOR, ANALGESICS, ANTIDEPRESSANT, ANTIDIARRHEA, OR HYPOTENSIVE AGENT | ROQUES BERNARD (FR) | 1986-10-21 | — | — | US | disclosed |